Medical Device Evaluation Center (MDEC) is a non-profit entity in Salt Lake City, Utah (USA) dedicated to medical research, health education, and other philanthropic activities intended to support local and global programs to improve education, healthcare, and other community-specific needs.
Click here for some more detailed information on MDEC's philanthropic activities in conjunction with SEVA in India. If you wish to contribute in some way to MDEC's research and philanthropic mission please call or email:
info@mdecnet.org
801-906-8595
MDEC's research activities are generally related to medical device hemocompatibility. An adverse consequence of using biomaterials in blood-contacting devices is the deposition of platelets and clotting proteins onto the biomaterial interface. Continued deposition of these components may lead to the formation of a thrombus. In addition to surface chemistry, non-laminar flow conditions play a role in thrombosis. Regions of disturbed flow are associated with most devices. Such regions are routinely accompanied by flow separation, stagnation, reattachment zones and high shear stress - all of which may lead to thrombosis. In collaboration with academia, scientists at MDEC are advancing the scientific understanding of such phenomena.
Click the image to play a short clip of thrombus forming in a flow cell
resembling regions of flow disturbance in certain blood-contacting devices.
(opens a new tab or window)
Video clip provided courtesy of Dr. Ken Solen in the Chemical Engineering Department,
Brigham Young University, Provo, Utah (USA)
MDEC no longer conducts device testing for the medical device industry. For industry sponsored studies related to device thrombosis and hemocompatibility, you can visit thrombodyne.com or contact: Dr. Sivaprasad "SP" Sukavaneshvar, Ph.D.